The Nootropic Stack
Semax for drive and attention, Selank for the edge it takes off. Studied side by side for decades in Russia.
Nasal, not subcutaneous. The sets include everything for it.
- Duration
- 4 weeks
- Suits
- Complete beginners
The schedule
Semax
300–600 mcg- Frequency
- Daily
- When
- Morning, intranasal
Intranasal. Split between nostrils. Studied for attention and memory retention.
Selank
250–500 mcg- Frequency
- Daily
- When
- Afternoon, intranasal
Intranasal. Studied for anxiolytic effect without sedation, which is why it sits later in the day than Semax.
Order this protocol
Everything in the schedule, in one order. Options where the protocol offers a choice.
View the protocol set →Why the pair
Semax raises BDNF and modulates dopamine — research associates it with attention and memory retention. Used alone it can feel like a stimulant without the stimulant, which suits some people and overshoots for others.
Selank works on GABA and serotonin signalling, and research reports reduced anxiety without sedation. Running them together is how they were studied: one raises drive, the other keeps it from tipping into agitation.
Why nasal
Both are peptides that cross into the central nervous system, and both were developed for intranasal administration. That is how the Russian clinical work was done, and it avoids injecting for a compound whose target is the brain.
The sets include the spray bottle, NSS and bacteriostatic water, because none of it works without all of it.
What the research supports
There is a substantial Russian literature on both, spanning decades. Very little of it has been replicated in Western trials, which is the honest caveat: the evidence base is real but geographically narrow, and translation quality varies.
Practical notes
Four weeks on is the common research window, then a break. Store the made-up spray refrigerated.
Schedules describe how these compounds are used in the research literature. They are not medical advice, and nothing here is for human consumption.